Monday, August 5, 2019

Python-machine learning auto data

Python, pandas and numpy installation
solves the problem

C:\> setx PATH "%PATH%;C:\<path\to\python\folder>\Scripts"
C:\> pip install pandas
I wasted time to find out the correct url link:
url = "https://archive.ics.uci.edu/ml/machine-learning-databases/autos/imports-85.data"

Thursday, February 14, 2019

BLAST-Basic Local Alignment Search Tool

Standalone BLAST on Linux machine:

BLAST detects regions of local similarities between sequences.

  • How to Create your own database and search for the desired sequence?
  1. First way is wget on command line;
which is $   wget ftp://ftp.ncbi.nih.gov/blast/db/FASTA/nr.gz
      $ wget -c ftp://ftp.ncbi.nih.gov/blast/db/FASTA/nr.gz 
-c means to continue
  1. NCBI ftp website 

Thursday, January 3, 2019

notes on Drummond et al "Why highly expressed proteins evolve slowly" paper

Some stuff:


30 years ago, Zuckerkandl proposed that a protein’s sequence will evolve at a rate primarily determined by the proportion of its sites involved in specific functions (or ‘‘functional density’’).
However, those effects in functional density and measurements of residues in protein functions remained unclear.


Wednesday, January 2, 2019

gene duplication in bacteria

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787491/pdf/1745-6150-4-46.pdf

Nice article.