notes on Drummond et al "Why highly expressed proteins evolve slowly" paper

Some stuff:

30 years ago, Zuckerkandl proposed that a protein’s sequence will evolve at a rate primarily determined by the proportion of its sites involved in specific functions (or ‘‘functional density’’).

However, those effects in functional density and measurements of residues in protein functions remained unclear.

gene duplication in bacteria

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787491/pdf/1745-6150-4-46.pdf

Nice article.